BS8416

antibody from Bioworld Technology, Inc
Targeting: SUFU PRO1280, SUFUH, SUFUXL
Provider product page for BS8416
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8416 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SUFU polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SUFU.
Description
Su(fu) (for Suppressor-of-Fused) is a key negative regulator in the vertebrate Hedgehog signaling pathway. Su(fu) interacts with genes encoding proteins in this signal transduction pathway. In Drosophila, Intracellular transduction of the Hedgehog pathway involves the release of a large complex containing Su(fu). Su(fu) inhibits the activity of the transcription factor Gli1 and interacts with Gli2, Gli3 and the serine/threonine kinase Fused. Su(fu) is widely expressed in adult and embryonic tissues with higher expression in tissues patterned by hegdehog signaling. The Su(fu) gene locus maps to a region that is deleted in glioblastomas, prostate cancer, malignant melanoma and endometrial cancer.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SUFU protein structure - BS8416 shown in red.