APR04436G

antibody from Leading Biology

Targeting: LRRC8A FLJ10337, KIAA1437, LRRC8, SWELL1

Western blot (Recommended by provider)

Antibody Data

Product number

APR04436G

Provider

Leading Biology

Product name

LRRC8A Antibody(C-term)

Antibody type

Polyclonal

Description

This gene encodes a protein belonging to the leucine-richrepeat family of proteins, which are involved in diverse biologicalprocesses, including cell adhesion, cellular trafficking, andhormone-receptor interactions. This family member is a putativefour-pass transmembrane protein that plays a role in B celldevelopment. Defects in this gene cause autosomal dominantnon-Bruton type agammaglobulinemia, an immunodeficiency diseaseresulting from defects in B cell maturation. Multiple alternativelyspliced transcript variants, which encode the same protein, havebeen identified for this gene.

Reactivity

Human, Mouse

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.