ADI-AAP-300-E

antibody from Enzo Life Sciences

Targeting: APAF1 APAF-1, CED4

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ADI-AAP-300-E

Provider

Enzo Life Sciences

Product name

Apaf-1 polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Peptide affinity purified.

Reactivity

Human, Mouse, Rat, Chicken/Avian

Host

Rabbit

Vial size

100 μg

Storage

+4°C

References

Submitted references

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim.

Szegezdi E, Herbert KR, Kavanagh ET, Samali A, Gorman AM
Journal of cellular and molecular medicine 2008 Dec;12(6A):2482-96

---

Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation.

Troy CM, Rabacchi SA, Hohl JB, Angelastro JM, Greene LA, Shelanski ML
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001 Jul 15;21(14):5007-16

---

The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis.

Lauber K, Appel HA, Schlosser SF, Gregor M, Schulze-Osthoff K, Wesselborg S
The Journal of biological chemistry 2001 Aug 10;276(32):29772-81

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Western blot analysis of Apaf1 in K562 cell lysate with Apaf1 antibody at 1µg/ml in the (A) absence and (B) presence of blocking peptide.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunohistochemistry analysis of Apaf1 in human heart tissue with Apaf1 antibody at 1µg/ml.