FNab09046

antibody from FineTest Biotech
Targeting: TSHZ3 KIAA1474, TSH3, ZNF537
Provider product page for FNab09046
Western blot
ELISA

Antibody data

Product number
FNab09046 - Provider product page
Provider
FineTest Biotech
Product name
TSHZ3 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus(nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator(RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
teashirt zinc finger homeobox 3
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
TSHZ3 protein structure - FNab09046 shown in red.