Tissue expression
Cell line expression
Protein structure
IRF5
Interferon regulatory factor 5This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
35 references | Polyclonal |
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Novus Biologicals | ![]() |
2 references | Monoclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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LSBio | ![]() |
Monoclonal |
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OriGene | ![]() |
Monoclonal |
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