14-1206-80

antibody from Invitrogen Antibodies
Targeting: IL20RB DIRS1, FNDC6, IL-20R2, MGC34923
Provider product page for 14-1206-80
Western blot
Immunocytochemistry
Flow cytometry
Other assay

Antibody data

Product number
14-1206-80 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-IL-20RB Monoclonal Antibody (20RNTC), eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi. Applications Reported: This 20RNTC antibody has been reported for use in immunocytochemistry, immunoblotting (WB) and flow cytometric analysis. Applications Tested: This 20RNTC antibody has been tested by immunofluorescent staining and flow cytometric analysis of fixed and permeabilized A375 cells. This can be used between 1-10 µg/mL. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human, Mouse
Host
Rat
Isotype
IgG
Antibody clone number
20RNTC
Vial size
25 µg
Concentration
0.5 mg/mL
Storage
4° C
IL20RB protein structure - 14-1206-80 shown in red.