BS7179

antibody from Bioworld Technology, Inc
Targeting: NRF1 ALPHA-PAL, EWG
Provider product page for BS7179
Western blot
Immunohistochemistry

Antibody data

Product number
BS7179 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NRF 1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NRF-1.
Description
Nuclear respiratory factor-1 (NRF-1) is a transcriptional activator that has been implicated in the nuclear control of respiratory chain expression in mammalian cells. The NRF-1 gene is expressed during oogenesis and during the early stages of embryogenesis. In vitro studies have implicated NRF-1 in the transcriptional expression of nuclear genes required for mitochondrial respiratory function, as well as for other fundamental cellular activities. While most isolated wild-type and NRF-1+/- blastocysts continue to develop normally in vitro, NRF-1-/- blastocysts lack this ability, despite their normal morphology. NRF-1 is specifically required in the maintenance of mtDNA and respiratory chain function during early embryogenesis. NRF-1 also plays a key role in cellular adaptation to energy demands by translating physiological signals into an increased capacity for generating energy.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NRF1 protein structure - BS7179 shown in red.