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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2508 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2508, RRID:AB_1579054
- Product name
- PPT1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PPT1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2.
The neuronal ceroid lipofuscinoses: mutations in different proteins result in similar disease.
Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2).
Calero G, Gupta P, Nonato MC, Tandel S, Biehl ER, Hofmann SL, Clardy J
The Journal of biological chemistry 2003 Sep 26;278(39):37957-64
The Journal of biological chemistry 2003 Sep 26;278(39):37957-64
The neuronal ceroid lipofuscinoses: mutations in different proteins result in similar disease.
Weimer JM, Kriscenski-Perry E, Elshatory Y, Pearce DA
Neuromolecular medicine 2002;1(2):111-24
Neuromolecular medicine 2002;1(2):111-24
Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2).
Hofmann SL, Atashband A, Cho SK, Das AK, Gupta P, Lu JY
Current molecular medicine 2002 Aug;2(5):423-37
Current molecular medicine 2002 Aug;2(5):423-37
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PPT1 polyclonal antibody (Cat # PAB2508) is used in Western blot to detect PPT1 in 293 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the PPT1 polyclonal antibody (Cat # PAB2508) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
