MTA2

gene product
MTA1-L1, MTA1L1
This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
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153 antibodies from 19 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Santa Cruz Biotechnology
2 antibodies
Bethyl Laboratories, Inc.
2 antibodies
antibodies-online
65 antibodies
Aviva Systems Biology
10 antibodies
Novus Biologicals
5 antibodies
Abnova Corporation
5 antibodies
Thermo Fisher Scientific Pierce
6 antibodies
Atlas Antibodies
1 antibody
Acris Antibodies GmbH
7 antibodies
GeneTex
3 antibodies
ProSci
1 antibody
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
18 antibodies
RabMAbs
3 antibodies
Creative Biomart
12 antibodies
Sigma-Aldrich
7 antibodies
Abiocode, Inc.
1 antibody
GenWay
3 antibodies
Active Motif
1 antibody