BS5820

antibody from Bioworld Technology, Inc
Targeting: NPAS1 bHLHe11, MOP5, PASD5
Provider product page for BS5820

Antibody data

Product number
BS5820 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NPAS1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 486-531 of Human NPAS1.
Description
Members of the bHLH-PAS family are transcription factors that contain a basic helix-loop-helix (bHLH) DNA-recognition motif which is located N-terminal to a PAS domain comprised of two imperfect direct repeats. Human NPAS1 is a deduced 590-amino acid protein which shares 86% sequence homology with mouse Npas1. In order for NPAS1 to bind DNA efficiently, it must form a dimer with another bHLH protein. NPAS1 interacts with ARNT (aryl hydrocarbon receptor nuclear translocator), and shows predominant expression in brain tissue. NPAS1 is also implicated in the control of regulatory pathways relevant to schizophrenia and to psychotic illness, and may play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen levels.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NPAS1 protein structure - BS5820 shown in red.