BS6032

antibody from Bioworld Technology, Inc

Targeting: STEAP3 dudlin-2, STMP3, TSAP6

Immunohistochemistry

Antibody data

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Validation data

Product number: BS6032 - Provider product page
Provider: Bioworld Technology, Inc
Product name: STEAP3 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human STEAP3.
Description: pHyde has a potential role as a tumor suppressor by inducing caspase-3-mediated apoptosis and stimulating p53 expression. A dose-dependent increase in caspase-3 activity is observed in transduced pHyde DU145 cells. Furthermore, caspase-3 may be necessary for pHyde-mediated apoptosis. The pHyde gene may upregulate the apoptosis pathway and thus have a potential application in cancer gene therapy. Recombinant pHyde inhibits the growth of human prostate cancer cell lines DU145 and LNCaP in vitro. DU145 tumors may be reduced significantly in vivo when nude mice are injected with recombinant pHyde. pHyde also has a demonstrated growth inhibitory effect on human breast cancer cells. This suggests that pHyde may have a role in inhibiting different tumor types.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

STEAP3 protein structure - BS6032 shown in red.