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- Antigen structure
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- Immunohistochemistry [1]
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- Product number
- ABIN952725 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 201-230), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 201-230, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland.
T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA.
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
Ogba N, Doughman YQ, Chaplin LJ, Hu Y, Gargesha M, Watanabe M, Montano MM
Oncogene 2010 Jun 24;29(25):3639-49
Oncogene 2010 Jun 24;29(25):3639-49
T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
Dow EC, Liu H, Rice AP
Journal of cellular physiology 2010 Jul;224(1):84-93
Journal of cellular physiology 2010 Jul;224(1):84-93
Specificity of Hexim1 and Hexim2 complex formation with cyclin T1/T2, importin alpha and 7SK snRNA.
Czudnochowski N, Vollmuth F, Baumann S, Vogel-Bachmayr K, Geyer M
Journal of molecular biology 2010 Jan 8;395(1):28-41
Journal of molecular biology 2010 Jan 8;395(1):28-41
A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.
Schönichen A, Bigalke JM, Urbanke C, Grzesiek S, Dames SA, Geyer M
Biochemistry 2010 Apr 13;49(14):3083-91
Biochemistry 2010 Apr 13;49(14):3083-91
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
