Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN968693 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Ligase III, DNA, ATP-Dependent (LIG3) (AA 2-115) antibody
- Antibody type
- Monoclonal
- Antigen
- Human DNA Ligase III
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 2-115
- Isotype
- IgG
- Antibody clone number
- 7
- Vial size
- 150 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references The DNA ligase III zinc finger stimulates binding to DNA secondary structure and promotes end joining.
ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose).
DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.
Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination.
Taylor RM, Whitehouse CJ, Caldecott KW
Nucleic acids research 2000 Sep 15;28(18):3558-63
Nucleic acids research 2000 Sep 15;28(18):3558-63
ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose).
Oei SL, Ziegler M
The Journal of biological chemistry 2000 Jul 28;275(30):23234-9
The Journal of biological chemistry 2000 Jul 28;275(30):23234-9
DNA ligase III is recruited to DNA strand breaks by a zinc finger motif homologous to that of poly(ADP-ribose) polymerase. Identification of two functionally distinct DNA binding regions within DNA ligase III.
Mackey ZB, Niedergang C, Murcia JM, Leppard J, Au K, Chen J, de Murcia G, Tomkinson AE
The Journal of biological chemistry 1999 Jul 30;274(31):21679-87
The Journal of biological chemistry 1999 Jul 30;274(31):21679-87
Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination.
Chen J, Tomkinson AE, Ramos W, Mackey ZB, Danehower S, Walter CA, Schultz RA, Besterman JM, Husain I
Molecular and cellular biology 1995 Oct;15(10):5412-22
Molecular and cellular biology 1995 Oct;15(10):5412-22
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