Tissue expression
Cell line expression
Protein structure
MECOM
MDS1 and EVI1 complex locusEVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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Atlas Antibodies | ![]() |
2 references | Polyclonal |
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Cell Signaling Technology, Inc | ![]() |
1 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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Novus Biologicals | ![]() |
3 references | Polyclonal |
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