TSKS

This gene may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression. [provided by RefSeq, Jul 2008]

Description

Testis specific serine kinase substrate

Tissue specificity

Tissue enriched (testis)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

19 (49739753 - 49763306)

Ensembl ID

ENSG00000126467  (ver. 103.38)

Orthologs

Mouse Tsks: ENSMUSG00000059891

UniProt

Q9UJT2

neXtProt

NX_Q9UJT2

Human splice variants
Mouse splice variants

Protein structure