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antibody from Novus Biologicals
Targeting: GZMB
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- AF1865 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Granzyme B Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse Granzyme B in ELISAs and Western blots. In sandwich immunoassays, less than 1% cross-reactivity with recombinant human (rh) rhGranzyme A, rhGranzyme B, recombinant mouse (rm) Granzyme D, rmGranzyme G, and rhGranzyme H is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references PARP Inhibitor Efficacy Depends on CD8(+) T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer.
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.
Novel recombinant DNA vaccine candidates for human respiratory syncytial virus: Preclinical evaluation of immunogenicity and protection efficiency.
Human papillomavirus (HPV) type 16 E7 protein bodies cause tumour regression in mice.
Endogenous retinoids in the pathogenesis of alopecia areata.
Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules.
Pantelidou C, Sonzogni O, De Oliveria Taveira M, Mehta AK, Kothari A, Wang D, Visal T, Li MK, Pinto J, Castrillon JA, Cheney EM, Bouwman P, Jonkers J, Rottenberg S, Guerriero JL, Wulf GM, Shapiro GI
Cancer discovery 2019 Jun;9(6):722-737
Cancer discovery 2019 Jun;9(6):722-737
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.
Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO, Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC
The Journal of clinical investigation 2019 Jul 15;129(8):3324-3338
The Journal of clinical investigation 2019 Jul 15;129(8):3324-3338
Novel recombinant DNA vaccine candidates for human respiratory syncytial virus: Preclinical evaluation of immunogenicity and protection efficiency.
Farrag MA, Amer HM, Öhlschläger P, Hamad ME, Almajhdi FN
Human vaccines & immunotherapeutics 2017 Jul 3;13(7):1586-1597
Human vaccines & immunotherapeutics 2017 Jul 3;13(7):1586-1597
Human papillomavirus (HPV) type 16 E7 protein bodies cause tumour regression in mice.
Whitehead M, Ohlschläger P, Almajhdi FN, Alloza L, Marzábal P, Meyers AE, Hitzeroth II, Rybicki EP
BMC cancer 2014 May 24;14:367
BMC cancer 2014 May 24;14:367
Endogenous retinoids in the pathogenesis of alopecia areata.
Duncan FJ, Silva KA, Johnson CJ, King BL, Szatkiewicz JP, Kamdar SP, Ong DE, Napoli JL, Wang J, King LE Jr, Whiting DA, McElwee KJ, Sundberg JP, Everts HB
The Journal of investigative dermatology 2013 Feb;133(2):334-43
The Journal of investigative dermatology 2013 Feb;133(2):334-43
Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules.
Zhang M, Park SM, Wang Y, Shah R, Liu N, Murmann AE, Wang CR, Peter ME, Ashton-Rickardt PG
Immunity 2006 Apr;24(4):451-61
Immunity 2006 Apr;24(4):451-61
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Granzyme B in Mouse Spleen Tissue. Granzyme B in Mouse Spleen Tissue.
