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antibody from BioLegend
Targeting: GZMB
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Flow cytometry [1]
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- Product number
- 515405 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#515405, RRID:AB_2294995
- Product name
- Alexa Fluor® 647 anti-human/mouse Granzyme B [GB11]
- Antibody type
- Monoclonal
- Antigen
- Granzyme B
- Description
- Granzyme B is a 32 kD serine protease, also known as granzyme-2, serine protease B, CCP1, Asp-ase, and CTLA-1. Granzyme B is abundantly stored in the granules of cytotoxic T lymphocytes and NK cells. Low level of expression has been reported in granulocytes, B cells and activated dendritic cells. Granzyme B is crucial for rapid induction of cell death and apoptosis through interaction with mannose-6-phosphate receptor.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes surface stained with CD8 PE, then intracellular stained with mouse IgG1 Alexa Fluor® 647 isotype control
- Conjugate
- Red dye
