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TBX5
T-box transcription factor 5HOS
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-29845 |
2 references | Polyclonal |
WB
ICC
IHC
OA
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| Novus Biologicals | H00006910-M01 |
3 references | Monoclonal |
WB
EL
ICC
BN
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| Proteintech Group | 13178-1-AP |
11 references | Polyclonal |
WB
EL
ICC
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| LSBio | LS-C403327 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN556633 |
Polyclonal |
WB
ICC
IHC
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