Tissue expression
Cell line expression
Protein structure
PARL
Presenilin associated rhomboid likePRO2207, PSARL, PSARL1, RHBDS1
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016]
Top validated antibodies |
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antibodies-online | ABIN2869331 | 3 references | Monoclonal |
WB
EL
ICC
IHC |
|
LSBio | LS-B5095 | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP1-44262 | 2 references | Polyclonal |
WB
EL
ICC
IHC |
|
Proteintech Group | 26679-1-AP | 1 references | Polyclonal |
WB
EL
IHC
|
|
Abnova Corporation | PAB13061 | 3 references | Polyclonal |
WB
ICC |
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Supportive data in Antibodypedia
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Recommended by provider