Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15059-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15059-1-AP, RRID:AB_10638622
- Product name
- HPRT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HPRT1 antibody (Cat. #15059-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages.
HPRT promotes proliferation and metastasis in head and neck squamous cell carcinoma through direct interaction with STAT3.
Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.
Uteroplacental Insufficiency Impairs Cholesterol Elimination in Adult Female Growth-Restricted Rat Offspring Fed a High-Fat Diet.
Impact of diet on the persistence of early vascular remodeling and stiffening induced by intrauterine growth restriction and a maternal high-fat diet.
Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1.
Intrauterine growth restriction combined with a maternal high-fat diet increased adiposity and serum corticosterone levels in adult rat offspring.
Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.
Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.
Intrauterine growth restriction combined with a maternal high-fat diet increases hepatic cholesterol and low-density lipoprotein receptor activity in rats.
Generation of Hprt-disrupted rat through mouse←rat ES chimeras.
Combination of intrauterine growth restriction and a high-fat diet impairs cholesterol elimination in rats.
Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response.
Wu G, Suo C, Yang Y, Shen S, Sun L, Li ST, Zhou Y, Yang D, Wang Y, Cai Y, Wang N, Zhang H, Yang YG, Cao J, Gao P
EMBO reports 2021 Mar 3;22(3):e51519
EMBO reports 2021 Mar 3;22(3):e51519
Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages.
Navarro-Guerrero E, Tay C, Whalley JP, Cowley SA, Davies B, Knight JC, Ebner D
Scientific reports 2021 Feb 19;11(1):4245
Scientific reports 2021 Feb 19;11(1):4245
HPRT promotes proliferation and metastasis in head and neck squamous cell carcinoma through direct interaction with STAT3.
Wang L, Wang Y, Han N, Wang X, Ruan M
Experimental cell research 2021 Feb 1;399(1):112424
Experimental cell research 2021 Feb 1;399(1):112424
Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.
Fil D, Chacko BK, Conley R, Ouyang X, Zhang J, Darley-Usmar VM, Zuberi AR, Lutz CM, Napierala M, Napierala JS
Disease models & mechanisms 2020 Jul 27;13(7)
Disease models & mechanisms 2020 Jul 27;13(7)
Uteroplacental Insufficiency Impairs Cholesterol Elimination in Adult Female Growth-Restricted Rat Offspring Fed a High-Fat Diet.
Zinkhan EK, Yu B, McKnight R
Reproductive sciences (Thousand Oaks, Calif.) 2019 Sep;26(9):1173-1180
Reproductive sciences (Thousand Oaks, Calif.) 2019 Sep;26(9):1173-1180
Impact of diet on the persistence of early vascular remodeling and stiffening induced by intrauterine growth restriction and a maternal high-fat diet.
Miller TA, Dodson RB, Mankouski A, Powers KN, Yang Y, Yu B, Zinkhan EK
American journal of physiology. Heart and circulatory physiology 2019 Aug 1;317(2):H424-H433
American journal of physiology. Heart and circulatory physiology 2019 Aug 1;317(2):H424-H433
Prenatal Exposure to a Maternal High Fat Diet Increases Hepatic Cholesterol Accumulation in Intrauterine Growth Restricted Rats in Part Through MicroRNA-122 Inhibition of Cyp7a1.
Zinkhan EK, Yu B, Schlegel A
Frontiers in physiology 2018;9:645
Frontiers in physiology 2018;9:645
Intrauterine growth restriction combined with a maternal high-fat diet increased adiposity and serum corticosterone levels in adult rat offspring.
Zinkhan EK, Yu B, Callaway CW, McKnight RA
Journal of developmental origins of health and disease 2018 Jun;9(3):315-328
Journal of developmental origins of health and disease 2018 Jun;9(3):315-328
Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.
Shavlakadze T, Zhu J, Wang S, Zhou W, Morin B, Egerman MA, Fan L, Wang Y, Iartchouk O, Meyer A, Valdez RA, Mannick JB, Klickstein LB, Glass DJ
The journals of gerontology. Series A, Biological sciences and medical sciences 2018 Jun 14;73(7):845-852
The journals of gerontology. Series A, Biological sciences and medical sciences 2018 Jun 14;73(7):845-852
Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.
Yang X, Park SH, Chang HC, Shapiro JS, Vassilopoulos A, Sawicki KT, Chen C, Shang M, Burridge PW, Epting CL, Wilsbacher LD, Jenkitkasemwong S, Knutson M, Gius D, Ardehali H
The Journal of clinical investigation 2017 Apr 3;127(4):1505-1516
The Journal of clinical investigation 2017 Apr 3;127(4):1505-1516
Intrauterine growth restriction combined with a maternal high-fat diet increases hepatic cholesterol and low-density lipoprotein receptor activity in rats.
Zinkhan EK, Zalla JM, Carpenter JR, Yu B, Yu X, Chan G, Joss-Moore L, Lane RH
Physiological reports 2016 Jul;4(13)
Physiological reports 2016 Jul;4(13)
Generation of Hprt-disrupted rat through mouse←rat ES chimeras.
Isotani A, Yamagata K, Okabe M, Ikawa M
Scientific reports 2016 Apr 11;6:24215
Scientific reports 2016 Apr 11;6:24215
Combination of intrauterine growth restriction and a high-fat diet impairs cholesterol elimination in rats.
Zinkhan EK, Chin JR, Zalla JM, Yu B, Numpang B, Yu X, Jiang C, Callaway CW, McKnight RA, Joss-Moore L, Lane RH
Pediatric research 2014 Nov;76(5):432-40
Pediatric research 2014 Nov;76(5):432-40
Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response.
Owens GC, Huynh MN, Chang JW, McArthur DL, Hickey MJ, Vinters HV, Mathern GW, Kruse CA
Journal of neuroinflammation 2013 May 2;10:56
Journal of neuroinflammation 2013 May 2;10:56
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15059-1-AP(HPRT1 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using HPRT1 antibody 15059-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15059-1-AP(HPRT1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15059-1-AP(HPRT1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue