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antibody from antibodies-online
Targeting: HCAR2
GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- ABIN952597 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Hydroxycarboxylic Acid Receptor 2 (HCAR2) (AA 207-236), (Middle Region) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 207-236, Middle Region
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.
Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.
Evidence for constitutive dimerization of niacin receptor subtypes.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.
Li X, Millar JS, Brownell N, Briand F, Rader DJ
Biochemical pharmacology 2010 Nov 1;80(9):1450-7
Biochemical pharmacology 2010 Nov 1;80(9):1450-7
Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.
Shen HC, Ding FX, Raghavan S, Deng Q, Luell S, Forrest MJ, Carballo-Jane E, Wilsie LC, Krsmanovic ML, Taggart AK, Wu KK, Wu TJ, Cheng K, Ren N, Cai TQ, Chen Q, Wang J, Wolff MS, Tong X, Holt TG, Waters MG, Hammond ML, Tata JR, Colletti SL
Journal of medicinal chemistry 2010 Mar 25;53(6):2666-70
Journal of medicinal chemistry 2010 Mar 25;53(6):2666-70
Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.
Li G, Shi Y, Huang H, Zhang Y, Wu K, Luo J, Sun Y, Lu J, Benovic JL, Zhou N
The Journal of biological chemistry 2010 Jul 16;285(29):22605-18
The Journal of biological chemistry 2010 Jul 16;285(29):22605-18
Evidence for constitutive dimerization of niacin receptor subtypes.
Mandrika I, Petrovska R, Klovins J
Biochemical and biophysical research communications 2010 Apr 30;395(2):281-7
Biochemical and biophysical research communications 2010 Apr 30;395(2):281-7
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