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- Antigen structure
- References [7]
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- Western blot [2]
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- Product number
- 21055-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21055-1-AP, RRID:AB_10695769
- Product name
- OXA1L antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated OXA1L antibody (Cat. #21055-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding.
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation.
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis.
OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.
Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number.
Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2.
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Shin CS, Meng S, Garbis SD, Moradian A, Taylor RW, Sweredoski MJ, Lomenick B, Chan DC
Nature communications 2021 Jan 11;12(1):265
Nature communications 2021 Jan 11;12(1):265
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation.
Perks KL, Ferreira N, Ermer JA, Rudler DL, Richman TR, Rossetti G, Matthews VB, Ward NC, Rackham O, Filipovska A
Aging 2020 Oct 6;12(19):19677-19700
Aging 2020 Oct 6;12(19):19677-19700
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis.
Lee RG, Gao J, Siira SJ, Shearwood AM, Ermer JA, Hofferek V, Mathews JC, Zheng M, Reid GE, Rackham O, Filipovska A
Journal of cell science 2020 Jul 24;133(14)
Journal of cell science 2020 Jul 24;133(14)
OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect.
Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW
EMBO molecular medicine 2018 Nov;10(11)
EMBO molecular medicine 2018 Nov;10(11)
Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number.
Thompson K, Majd H, Dallabona C, Reinson K, King MS, Alston CL, He L, Lodi T, Jones SA, Fattal-Valevski A, Fraenkel ND, Saada A, Haham A, Isohanni P, Vara R, Barbosa IA, Simpson MA, Deshpande C, Puusepp S, Bonnen PE, Rodenburg RJ, Suomalainen A, Õunap K, Elpeleg O, Ferrero I, McFarland R, Kunji ER, Taylor RW
American journal of human genetics 2016 Oct 6;99(4):860-876
American journal of human genetics 2016 Oct 6;99(4):860-876
Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2.
Chan NC, den Besten W, Sweredoski MJ, Hess S, Deshaies RJ, Chan DC
The Journal of biological chemistry 2014 Jul 11;289(28):19789-98
The Journal of biological chemistry 2014 Jul 11;289(28):19789-98
Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.
Mishra P, Carelli V, Manfredi G, Chan DC
Cell metabolism 2014 Apr 1;19(4):630-41
Cell metabolism 2014 Apr 1;19(4):630-41
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 21055-1-AP(OXA1L antibody) at dilution of 1:800
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The OXA1L antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human OXA1L. This antibody recognizes human,mouse,rat antigen. The OXA1L antibody has been validated for the following applications: ELISA, WB analysis.
