BS8352

antibody from Bioworld Technology, Inc
Targeting: PANX1 MRS1, PX1, UNQ2529
Provider product page for BS8352
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8352 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PANX1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PANX1.
Description
Gap junctions are formed by a hexameric group of proteins called connexins for the transport of low molecular weight proteins from cell to cell. Connexins, which are present in all metazoan organisms, serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. Several mammalian cells with malignant phenotypes exhibit decreased connexin expression and gap junction communication. The pannexin gene family encodes a second class of putative gap junction proteins. Pannexins are highly conserved in invertebrates and mammals, indicating the importance of their gap junctional coupling function. Mammalian Pannexin-1 and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. Pannexin-1 is a transmembrane protein that forms calcium-permeable gap junctions between adjacent cells and in the endoplasmic reticulum. In erythrocytes, Pannexin-1 forms a mechanosensitive ATP-permeable channel in the nonjunctional plasma membrane.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PANX1 protein structure - BS8352 shown in red.