FNab07100

antibody from FineTest Biotech
Targeting: RAN ARA24, Gsp1, TC4
Provider product page for FNab07100
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
FNab07100 - Provider product page
Provider
FineTest Biotech
Product name
RAN antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle(By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
RAN, member RAS oncogene family
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
RAN protein structure - FNab07100 shown in red.