PAB12883
antibody from Abnova Corporation
Targeting: NLRP2
CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB12883 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12883, RRID:AB_10553185
- Product name
- NLRP2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of NLRP2.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references NLRs join TLRs as innate sensors of pathogens.
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.
Martinon F, Tschopp J
Trends in immunology 2005 Aug;26(8):447-54
Trends in immunology 2005 Aug;26(8):447-54
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J
Immunity 2004 Mar;20(3):319-25
Immunity 2004 Mar;20(3):319-25
PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.
Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC
The Journal of biological chemistry 2004 Dec 10;279(50):51897-907
The Journal of biological chemistry 2004 Dec 10;279(50):51897-907
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of NARP2 in PC-3 cell lysate with NLRP2 polyclonal antibody (Cat # PAB12883) at 1 and 2 ug/mL .