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PDE11A
Phosphodiesterase 11AThe 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| GeneTex |  GTX14624 |
1 references | Polyclonal |
WB
IP
IHC
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| Invitrogen Antibodies | PA5-115727 |
Polyclonal |
WB
ICC
IHC
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| OriGene | AP08915PU-N |
Polyclonal |
WB
EL
IHC
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| Everest Biotech | EB07935 |
Polyclonal |
WB
EL
IHC
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| NovoPro Bioscience Inc. | 118371 |
Polyclonal |
WB
EL
IHC
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