CABT-B1837

antibody from Creative Diagnostics

Targeting: ACOX1 PALMCOX

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1837

Provider

Creative Diagnostics

Product name

Anti-ACOX1 polyclonal antibody

Antibody type

Polyclonal

Description

Peroxisomal acyl-coenzyme A oxidase 1 (AOX), also known as, Palmitoyl-CoA oxidase or Straight-chain acyl-CoA oxidase (SCOX), and encoded by the gene name(s), ACOX1 or ACOX, catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. ACOX1 donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. ACOX1 is localized to the peroxisome and is widely expressed. High expression of isoform 1 and isoform 2 are detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart. Mutations in ACOX1 result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Concentration

Please refer to lot specific datasheet.

Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.