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Cell line expression
Protein structure
MED23
Mediator complex subunit 23CRSP130, CRSP3, DRIP130, MRT18, Sur2
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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| Novus Biologicals |  NB200-337 |
5 references | Polyclonal |
WB
IP
ChIP
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| LSBio | LS-C368856 |
Polyclonal |
WB
ICC
IHC
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| Boster Biological Technology | A03859-2 |
Polyclonal |
WB
EL
ICC
IHC
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| Antibodies.com | A52598 |
Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN152372 |
5 references | Polyclonal |
WB
IP
ChIP
|
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