BS8103

antibody from Bioworld Technology, Inc
Targeting: DPEP1
Provider product page for BS8103
Western blot
Immunohistochemistry

Antibody data

Product number
BS8103 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DPEP1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DPEP1.
Description
DPEP1 (dipeptidase 1), also known as MDP, RDP or MBD1, is a 411 amino acid renal protein that localizes to the apical cell membrane and belongs to the peptidase M19 family. Existing as a disulfide-linked homodimer, DPEP1 uses zinc as a cofactor to catalyze the hydrolysis of various dipeptides and, via its catalytic activity, plays a role in glutathione and leukotriene metabolism. DPEP1 is functionally inhibited by L-penicillamine and is subject to post-translational N-glycosylation. The gene encoding DPEP1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DPEP1 protein structure - BS8103 shown in red.