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- References [2]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- NBP1-85455 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-85455, RRID:AB_11032160
- Product name
- Rabbit Polyclonal IL-22BP/IL22 RA2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human IL-22BP/IL22 RA2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Interleukin (IL)-22 receptor 1 is over-expressed in primary Sjogren's syndrome and Sjögren-associated non-Hodgkin lymphomas and is regulated by IL-18.
The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation.
Ciccia F, Guggino G, Rizzo A, Bombardieri M, Raimondo S, Carubbi F, Cannizzaro A, Sireci G, Dieli F, Campisi G, Giacomelli R, Cipriani P, De Leo G, Alessandro R, Triolo G
Clinical and experimental immunology 2015 Aug;181(2):219-29
Clinical and experimental immunology 2015 Aug;181(2):219-29
The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation.
Laaksonen H, Guerreiro-Cacais AO, Adzemovic MZ, Parsa R, Zeitelhofer M, Jagodic M, Olsson T
Genes and immunity 2014 Oct;15(7):457-65
Genes and immunity 2014 Oct;15(7):457-65
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: IL-22BP/IL22 RA2 Antibody [NBP1-85455] - Analysis in control (vector only transfected HEK293T lysate) and IL22RA2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: IL-22BP/IL22 RA2 Antibody [NBP1-85455] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: IL-22BP/IL22 RA2 Antibody [NBP1-85455] - Staining of human kidney shows moderate cytoplasmic staining and luminal membrane positivity in tubules.
