BS8570

antibody from Bioworld Technology, Inc
Targeting: DR1 NC2-BETA, NC2B, NCB2
Provider product page for BS8570
Western blot
Immunohistochemistry

Antibody data

Product number
BS8570 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DR1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Protein Dr1; Down-regulator of transcription 1; Negative cofactor 2-beta; NC2-beta; TATA-binding protein-associated phosphoprotein; DR1
Description
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DR1 protein structure - BS8570 shown in red.