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FZD7
Frizzled class receptor 7FzE3
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-C133983 |
Monoclonal |
WB
EL
IHC
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| Proteintech Group | 16974-1-AP |
12 references | Polyclonal |
WB
EL
IP
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| R&D Systems | AF198 |
5 references | Polyclonal |
WB
IHC
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| Novus Biologicals | AF198 |
5 references | Polyclonal |
WB
IHC
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| antibodies-online | ABIN710051 |
1 references | Polyclonal |
WB
ICC
IHC
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