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- Antibody Data
- Antigen structure
- References [30]
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- Product number
- MAB342 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human CD28 Monoclonal Antibody (Clone 37407)
- Antibody type
- Monoclonal
- Antigen
- S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD28, Asn19-Pro152
- Description
- Protein A or G purified from ascites
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P10747- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Humoral and cell-mediated immune responses after a booster dose of HBV vaccine in HIV-infected children, adolescents and young adults.
89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer.
Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.
Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue.
γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function.
High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function.
1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.
T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.
Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+ T-cell proliferation.
Neuropilin-1 expression characterizes T follicular helper (Tfh) cells activated during B cell differentiation in human secondary lymphoid organs.
A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis.
Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
Overlapping human leukocyte antigen class I/II binding peptide vaccine for the treatment of patients with stage IV melanoma: evidence of systemic immune dysfunction.
Suppression of immune responses in collagen-induced arthritis by a rationally designed CD80-binding peptide agent.
Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation.
Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation.
The association of Sam68 with Vav1 contributes to tumorigenesis.
The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysm.
Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Autoantibodies against CD28 are associated with atopic diseases.
Flow-cytometric analysis of cytokine production in human paracoccidioidomycosis.
Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay.
Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay.
Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis.
IL-22 increases the innate immunity of tissues.
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Giacomet V, Masetti M, Nannini P, Forlanini F, Clerici M, Zuccotti GV, Trabattoni D
PloS one 2018;13(2):e0192638
PloS one 2018;13(2):e0192638
89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer.
Bensch F, van der Veen EL, Lub-de Hooge MN, Jorritsma-Smit A, Boellaard R, Kok IC, Oosting SF, Schröder CP, Hiltermann TJN, van der Wekken AJ, Groen HJM, Kwee TC, Elias SG, Gietema JA, Bohorquez SS, de Crespigny A, Williams SP, Mancao C, Brouwers AH, Fine BM, de Vries EGE
Nature medicine 2018 Dec;24(12):1852-1858
Nature medicine 2018 Dec;24(12):1852-1858
Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.
Nakachi S, Sumitomo S, Tsuchida Y, Tsuchiya H, Kono M, Kato R, Sakurai K, Hanata N, Nagafuchi Y, Tateishi S, Kanda H, Okamura T, Yamamoto K, Fujio K
Arthritis research & therapy 2017 May 16;19(1):97
Arthritis research & therapy 2017 May 16;19(1):97
Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue.
Caër C, Rouault C, Le Roy T, Poitou C, Aron-Wisnewsky J, Torcivia A, Bichet JC, Clément K, Guerre-Millo M, André S
Scientific reports 2017 Jun 7;7(1):3000
Scientific reports 2017 Jun 7;7(1):3000
γδTCR immunoglobulin constant region domain exchange in human αβTCRs improves TCR pairing without altering TCR gene-modified T cell function.
Tao C, Shao H, Zhang W, Bo H, Wu F, Shen H, Huang S
Molecular medicine reports 2017 Apr;15(4):1555-1564
Molecular medicine reports 2017 Apr;15(4):1555-1564
High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function.
Foley MH, Forcier T, McAndrew E, Gonzalez M, Chen H, Juelg B, Walker BD, Irvine DJ
PloS one 2014;9(2):e87873
PloS one 2014;9(2):e87873
1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.
Van Belle TL, Vanherwegen AS, Feyaerts D, De Clercq P, Verstuyf A, Korf H, Gysemans C, Mathieu C
PloS one 2014;9(10):e109194
PloS one 2014;9(10):e109194
T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.
Dalmas E, Venteclef N, Caer C, Poitou C, Cremer I, Aron-Wisnewsky J, Lacroix-Desmazes S, Bayry J, Kaveri SV, Clément K, André S, Guerre-Millo M
Diabetes 2014 Jun;63(6):1966-77
Diabetes 2014 Jun;63(6):1966-77
Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+ T-cell proliferation.
Zhu L, Huang Z, Stålesen R, Hansson GK, Li N
Journal of thrombosis and haemostasis : JTH 2014 Jul;12(7):1156-65
Journal of thrombosis and haemostasis : JTH 2014 Jul;12(7):1156-65
Neuropilin-1 expression characterizes T follicular helper (Tfh) cells activated during B cell differentiation in human secondary lymphoid organs.
Renand A, Milpied P, Rossignol J, Bruneau J, Lemonnier F, Dussiot M, Coulon S, Hermine O
PloS one 2013;8(12):e85589
PloS one 2013;8(12):e85589
A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis.
Gironi M, Saresella M, Rovaris M, Vaghi M, Nemni R, Clerici M, Grossi E
Immunity & ageing : I & A 2013 Jan 10;10(1):1
Immunity & ageing : I & A 2013 Jan 10;10(1):1
Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
Clinical and experimental immunology 2009 Feb;155(2):266-74
Clinical and experimental immunology 2009 Feb;155(2):266-74
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Döcke WD, Asadullah K, Volk HD, Sterry W, Sabat R
European journal of immunology 2009 Dec;39(12):3570-81
European journal of immunology 2009 Dec;39(12):3570-81
Overlapping human leukocyte antigen class I/II binding peptide vaccine for the treatment of patients with stage IV melanoma: evidence of systemic immune dysfunction.
Melanoma Study Group of the Mayo Clinic Cancer Center., Celis E
Cancer 2007 Jul 1;110(1):203-14
Cancer 2007 Jul 1;110(1):203-14
Suppression of immune responses in collagen-induced arthritis by a rationally designed CD80-binding peptide agent.
Srinivasan M, Eri R, Zunt SL, Summerlin DJ, Brand DD, Blum JS
Arthritis and rheumatism 2007 Feb;56(2):498-508
Arthritis and rheumatism 2007 Feb;56(2):498-508
Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation.
Piconi S, Trabattoni D, Saresella M, Iemoli E, Schenal M, Fusi A, Borelli M, Chen L, Mascheri A, Clerici M
Journal of immunology (Baltimore, Md. : 1950) 2007 Feb 1;178(3):1931-7
Journal of immunology (Baltimore, Md. : 1950) 2007 Feb 1;178(3):1931-7
Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation.
Piconi S, Trabattoni D, Saresella M, Iemoli E, Schenal M, Fusi A, Borelli M, Chen L, Mascheri A, Clerici M
Journal of immunology (Baltimore, Md. : 1950) 2007 Feb 1;178(3):1931-7
Journal of immunology (Baltimore, Md. : 1950) 2007 Feb 1;178(3):1931-7
The association of Sam68 with Vav1 contributes to tumorigenesis.
Lazer G, Pe'er L, Schapira V, Richard S, Katzav S
Cellular signalling 2007 Dec;19(12):2479-86
Cellular signalling 2007 Dec;19(12):2479-86
The soluble forms of CD28, CD86 and CTLA-4 constitute possible immunological markers in patients with abdominal aortic aneurysm.
Sakthivel P, Shively V, Kakoulidou M, Pearce W, Lefvert AK
Journal of internal medicine 2007 Apr;261(4):399-407
Journal of internal medicine 2007 Apr;261(4):399-407
Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Bayry J, Triebel F, Kaveri SV, Tough DF
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4184-93
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4184-93
Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells.
Bayry J, Triebel F, Kaveri SV, Tough DF
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4184-93
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4184-93
Autoantibodies against CD28 are associated with atopic diseases.
Neuber K, Mähnss B, Hübner C, Gergely H, Weichenthal M
Clinical and experimental immunology 2006 Nov;146(2):262-9
Clinical and experimental immunology 2006 Nov;146(2):262-9
Flow-cytometric analysis of cytokine production in human paracoccidioidomycosis.
Mamoni RL, Blotta MH
Cytokine 2006 Aug;35(3-4):207-16
Cytokine 2006 Aug;35(3-4):207-16
Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay.
Ogilvie RL, Abelson M, Hau HH, Vlasova I, Blackshear PJ, Bohjanen PR
Journal of immunology (Baltimore, Md. : 1950) 2005 Jan 15;174(2):953-61
Journal of immunology (Baltimore, Md. : 1950) 2005 Jan 15;174(2):953-61
Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay.
Ogilvie RL, Abelson M, Hau HH, Vlasova I, Blackshear PJ, Bohjanen PR
Journal of immunology (Baltimore, Md. : 1950) 2005 Jan 15;174(2):953-61
Journal of immunology (Baltimore, Md. : 1950) 2005 Jan 15;174(2):953-61
Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
The Biochemical journal 2004 Jun 1;380(Pt 2):425-33
The Biochemical journal 2004 Jun 1;380(Pt 2):425-33
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis.
Janardhan A, Swigut T, Hill B, Myers MP, Skowronski J
PLoS biology 2004 Jan;2(1):E6
PLoS biology 2004 Jan;2(1):E6
IL-22 increases the innate immunity of tissues.
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity 2004 Aug;21(2):241-54
Immunity 2004 Aug;21(2):241-54
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Wolk K, Kunz S, Asadullah K, Sabat R
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Cutting edge: immune cells as sources and targets of the IL-10 family members?
Wolk K, Kunz S, Asadullah K, Sabat R
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
Journal of immunology (Baltimore, Md. : 1950) 2002 Jun 1;168(11):5397-402
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