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Protein structure
P3H2
Prolyl 3-hydroxylase 2FLJ10718, LEPREL1, MLAT4
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Top validated antibodies |
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| Proteintech Group |  15723-1-AP |
3 references | Polyclonal |
WB
EL
IP
IHC
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| Invitrogen Antibodies | 15723-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| NovoPro Bioscience Inc. | 112198 |
Polyclonal |
WB
EL
IP
IHC
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| FineTest Biotech | FNab04752 |
Polyclonal |
WB
EL
IP
IHC
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| Novus Biologicals | NBP1-94041 |
1 references | Polyclonal |
WB
IHC
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