ASPN

gene product
FLJ20129, PLAP1, SLRR1C
This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]
More gene data

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Supportive data in Antibodypedia
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Validated in Knockdown Initative
Eligible for validation in KDI
99 antibodies from 19 providers.

Antibody properties

Applications

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AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
7 antibodies
antibodies-online
31 antibodies
Acris Antibodies GmbH
4 antibodies
Invitrogen Antibodies
3 antibodies
OriGene
3 antibodies
Abgent
1 antibody
LifeSpan BioSciences, Inc.
9 antibodies
Aviva Systems Biology
3 antibodies
GeneTex
2 antibodies
Abnova Corporation
4 antibodies
Biorbyt
2 antibodies
Arigo
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
MyBioSource
5 antibodies
RabMAbs
1 antibody
United States Biological
14 antibodies
Sigma-Aldrich
4 antibodies
Creative Diagnostics
3 antibodies