HPA018142

antibody from Atlas Antibodies

Targeting: SETDB1 ESET, KG1T, KIAA0067, KMT1E, TDRD21

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA018142

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA018142, RRID:AB_1856757

Product name

Anti-SETDB1

Antibody type

Polyclonal

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

KLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDI
EDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWE
GTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTR
LEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKG
PVVQYTQD


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis.

Rodriguez-Paredes M, Martinez de Paz A, Simó-Riudalbas L, Sayols S, Moutinho C, Moran S, Villanueva A, Vázquez-Cedeira M, Lazo PA, Carneiro F, Moura CS, Vieira J, Teixeira MR, Esteller M
Oncogene 2014 May 22;33(21):2807-13

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The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.

Ceol CJ, Houvras Y, Jane-Valbuena J, Bilodeau S, Orlando DA, Battisti V, Fritsch L, Lin WM, Hollmann TJ, Ferré F, Bourque C, Burke CJ, Turner L, Uong A, Johnson LA, Beroukhim R, Mermel CH, Loda M, Ait-Si-Ali S, Garraway LA, Young RA, Zon LI
Nature 2011 Mar 24;471(7339):513-7

Immunocytochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, plasma membrane & cytosol.

Sample type

HUMAN

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human colon shows strong nuclear, cytoplasmic and membranous positivity in glandular cells.

Sample type

HUMAN