DPABH-09948

antibody from Creative Diagnostics
Targeting: GNE IBM2, Uae1
Provider product page for DPABH-09948
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
DPABH-09948 - Provider product page
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPABH-09948, RRID:AB_2511100
Product name
Rabbit Anti-Human GNE Polyclonal antibody
Antibody type
Polyclonal
Description
The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 uL
GNE protein structure - DPABH-09948 shown in red.