Tissue expression
Cell line expression
Protein structure
RGS18
Regulator of G protein signaling 18RGS13
This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NBP2-24417 | 1 references | Polyclonal |
WB
ICC |
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NSJ Bioreagents | RQ5759 | Polyclonal |
WB
EL
FC
|
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Proteintech Group | 11866-1-AP | 1 references | Polyclonal |
WB
EL |
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Boster Biological Technology | A10844-2 | Polyclonal |
WB
EL
FC
|
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Everest Biotech | EB06372 | Polyclonal |
WB
EL
IHC
|
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