Tissue expression
Cell line expression
Protein structure
KDM5B
Lysine demethylase 5BCT31, JARID1B, PLU-1, PPP1R98, RBBP2H1A
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Top validated antibodies |
|||||
Novus Biologicals | ![]() |
4 references | Monoclonal |
|
|
antibodies-online | ![]() |
7 references | Monoclonal |
|
|
Abnova Corporation | ![]() |
3 references | Monoclonal |
|
|
NSJ Bioreagents | ![]() |
Polyclonal |
|
||
Invitrogen Antibodies | ![]() |
Polyclonal |
|