abx015715

antibody from Abbexa

Targeting: TYRO3 Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

abx015715

Provider

Abbexa

Product name

Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3) Antibody

Antibody type

Monoclonal

Description

TYRO3: Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky.Entrez Protein: NP_006284.It belongs to the Tyr protein kinase family (AXL/UFO subfamily).The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl).Two distinct isoforms of Rse, designated Brt and Etk-2, have been described.Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence.It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface.Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence.Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.