21188-1-AP
antibody from Proteintech Group
Targeting: TAOK2
KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 21188-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21188-1-AP, RRID:AB_10755293
- Product name
- TAOK2 antibody
- Antibody type
- Polyclonal
- Description
- TAOK2 antibody (Cat. #21188-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Rnd3 interacts with TAO kinases and contributes to mitotic cell rounding and spindle positioning.
A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies.
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.
Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.
Garg R, Koo CY, Infante E, Giacomini C, Ridley AJ, Morris JDH
Journal of cell science 2020 Mar 16;133(6)
Journal of cell science 2020 Mar 16;133(6)
A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies.
Giacomini C, Koo CY, Yankova N, Tavares IA, Wray S, Noble W, Hanger DP, Morris JDH
Acta neuropathologica communications 2018 May 7;6(1):37
Acta neuropathologica communications 2018 May 7;6(1):37
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
Burns DT, Donkervoort S, Müller JS, Knierim E, Bharucha-Goebel D, Faqeih EA, Bell SK, AlFaifi AY, Monies D, Millan F, Retterer K, Dyack S, MacKay S, Morales-Gonzalez S, Giunta M, Munro B, Hudson G, Scavina M, Baker L, Massini TC, Lek M, Hu Y, Ezzo D, AlKuraya FS, Kang PB, Griffin H, Foley AR, Schuelke M, Horvath R, Bönnemann CG
American journal of human genetics 2018 May 3;102(5):858-873
American journal of human genetics 2018 May 3;102(5):858-873
Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.
Koo CY, Giacomini C, Reyes-Corral M, Olmos Y, Tavares IA, Marson CM, Linardopoulos S, Tutt AN, Morris JDH
Molecular cancer therapeutics 2017 Nov;16(11):2410-2421
Molecular cancer therapeutics 2017 Nov;16(11):2410-2421
Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.
Tavares IA, Touma D, Lynham S, Troakes C, Schober M, Causevic M, Garg R, Noble W, Killick R, Bodi I, Hanger DP, Morris JD
The Journal of biological chemistry 2013 May 24;288(21):15418-29
The Journal of biological chemistry 2013 May 24;288(21):15418-29
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The TAOK2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TAOK2. This antibody recognizes human,mouse,rat antigen. The TAOK2 antibody has been validated for the following applications: ELISA, WB analysis.