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LearnNB110-58771
antibody from Novus Biologicals
Targeting: LRRK2
DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- NB110-58771 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-58771, RRID:AB_921915
- Product name
- Rabbit Polyclonal LRRK2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.
Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies.
Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles.
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
Lrrk2 localization in the primate basal ganglia and thalamus: a light and electron microscopic analysis in monkeys.
Update on the functional biology of Lrrk2.
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
López de Maturana R, Lang V, Zubiarrain A, Sousa A, Vázquez N, Gorostidi A, Águila J, López de Munain A, Rodríguez M, Sánchez-Pernaute R
Journal of neuroinflammation 2016 Nov 18;13(1):295
Journal of neuroinflammation 2016 Nov 18;13(1):295
Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies.
Skibinski G, Nakamura K, Cookson MR, Finkbeiner S
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jan 8;34(2):418-33
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 Jan 8;34(2):418-33
Molecular markers for granulovacuolar degeneration are present in rimmed vacuoles.
Nakamori M, Takahashi T, Nishikawa T, Yamazaki Y, Kurashige T, Maruyama H, Arihiro K, Matsumoto M
PloS one 2013;8(11):e80995
PloS one 2013;8(11):e80995
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice.
Melrose HL, Dächsel JC, Behrouz B, Lincoln SJ, Yue M, Hinkle KM, Kent CB, Korvatska E, Taylor JP, Witten L, Liang YQ, Beevers JE, Boules M, Dugger BN, Serna VA, Gaukhman A, Yu X, Castanedes-Casey M, Braithwaite AT, Ogholikhan S, Yu N, Bass D, Tyndall G, Schellenberg GD, Dickson DW, Janus C, Farrer MJ
Neurobiology of disease 2010 Dec;40(3):503-17
Neurobiology of disease 2010 Dec;40(3):503-17
Lrrk2 localization in the primate basal ganglia and thalamus: a light and electron microscopic analysis in monkeys.
Lee H, Melrose HL, Yue M, Pare JF, Farrer MJ, Smith Y
Experimental neurology 2010 Aug;224(2):438-47
Experimental neurology 2010 Aug;224(2):438-47
Update on the functional biology of Lrrk2.
Melrose H
Future neurology 2008;3(6):669-681
Future neurology 2008;3(6):669-681
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Melrose HL, Kent CB, Taylor JP, Dachsel JC, Hinkle KM, Lincoln SJ, Mok SS, Culvenor JG, Masters CL, Tyndall GM, Bass DI, Ahmed Z, Andorfer CA, Ross OA, Wszolek ZK, Delldonne A, Dickson DW, Farrer MJ
Neuroscience 2007 Jul 29;147(4):1047-58
Neuroscience 2007 Jul 29;147(4):1047-58
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LRRK2 Antibody [NB110-58771] - NB110-58771 in increasing amounts of human lymphoblast
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: LRRK2 Antibody [NB110-58771] - DAB Immunostaining in frozen sections of mouse brainstem.
