FNab05720

antibody from FineTest Biotech

Targeting: NGEF ARHGEF27

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab05720 - Provider product page
Provider: FineTest Biotech
Product name: NGEF antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension(By similarity).
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: neuronal guanine nucleotide exchang e factor
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

NGEF protein structure - FNab05720 shown in red.