Tissue expression
Cell line expression
Protein structure
SH3BP1
SH3 domain binding protein 1ARHGAP43
This gene encodes a member of the Rho GTPase activating protein (RhoGAP) family. The encoded protein regulates Rac signaling and plays a role in cytoskeletal dynamics, cell motility and epithelial junction formation. This protein's association with the exocyst complex, which tethers secretory vesicles to the plasma membrane, has been demonstrated to be important in cell motility. In a distinct complex, this protein has been shown to regulate epithelial junction formation and morphogenesis. By interacting with the Plexin-D1 cell surface receptor, this protein mediates changes in the cytoskeleton in response to semaphorin binding. This protein may promote metastasis in human liver cancer cells and tissues. [provided by RefSeq, Mar 2017]
Top validated antibodies |
|||||
GeneTex | GTX107693 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
LSBio | LS-C185896 | Polyclonal |
WB
ICC
IHC
|
||
Invitrogen Antibodies | PA5-18249 | 1 references | Polyclonal |
WB
IHC
OA
|
|
Proteintech Group | 20541-1-AP | 1 references | Polyclonal |
WB
EL
ICC
|
|
Novus Biologicals | NB100-1398 | 1 references | Polyclonal |
WB
EL
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider