BS60266

antibody from Bioworld Technology, Inc
Targeting: CACNA1C CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS
Provider product page for BS60266

Antibody data

Product number
BS60266 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CACNA1C polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CACNA1C.
Description
Voltage-dependent Ca++ channels mediate Ca++ entryinto excitable cellsin response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, includingmuscle contraction, hormone or neurotransmitter release and gene expression. Calciumchannels are highly diverse,multimericcomplexescomposed of anÏ«-1 subunit, an intracellular ÉÇ-subunit, a disulfide linkedÏ«-2/Ñ´ subunit and a transmembrane ÎÛ-subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types.L-type Ca++ currentsinitiate muscle contraction, endocrine secretion, and gene transcription, and can be regulated through second-messenger activated protein phosphorylation pathways.L-type calcium channels may form macromolecular signaling complexeswith G protein-coupled receptors, thereby enhancing the selectivity of regulating specifictargets.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CACNA1C protein structure - BS60266 shown in red.