BS8289

antibody from Bioworld Technology, Inc
Targeting: GM2A SAP-3
Provider product page for BS8289
Western blot
Immunohistochemistry

Antibody data

Product number
BS8289 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GM2A polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GM2A.
Description
GM2-AP (GM2 ganglioside activator), also known as GM2A or SAP-3 (shingolipid activator protein 3), is a 193 amino acid protein that localizes to the lysosome. Existing as a small glycolipid transport protein, GM2-AP acts as a ganglioside-specific cofactor that, together with beta-hexosaminidase A (HEXA), stimulates the breakdown of glycolipid GA2 and ganglioside GM2 and is important for the degradation of proteins containing terminal N-acetyl hexosamines. Mutations in the gene encoding GM2-AP are the cause of GM2-gangliosidosis type AB (GM2GAB), which is also known as Tay-Sachs disease AB variant, and is an autosomal recessive disease that is characterized by ganglioside GM2 accumulation in the presence of both hexosaminidase A and B.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GM2A protein structure - BS8289 shown in red.