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Protein structure
GAK
Cyclin G associated kinaseDNAJC26
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Top validated antibodies |
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| LSBio |  LS-C101155 |
Polyclonal |
WB
IHC
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| Invitrogen Antibodies | H00002580-M01 |
Monoclonal |
WB
EL
IP
OA
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| Proteintech Group | 12147-1-AP |
1 references | Polyclonal |
WB
EL
ICC
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| Abnova Corporation | PAB3266 |
3 references | Polyclonal |
WB
IHC
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| antibodies-online | ABIN2837848 |
1 references | Polyclonal |
WB
IHC
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