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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11870-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11870-1-AP, RRID:AB_2215230
- Product name
- VPS37A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated VPS37A antibody (Cat. #11870-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
HCRP-1 regulates cell migration, invasion and angiogenesis via Src/ FAK signaling in human prostate cancer.
MicroRNA-19a acts as a prognostic marker and promotes prostate cancer progression via inhibiting VPS37A expression.
HCRP-1 regulates EGFR-AKT-BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer.
HCRP1 downregulation confers poor prognosis and induces chemoresistance through regulation of EGFR-AKT pathway in human gastric cancer.
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex.
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis.
UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting.
Kazan JM, Desrochers G, Martin CE, Jeong H, Kharitidi D, Apaja PM, Roldan A, St Denis N, Gingras AC, Lukacs GL, Pause A
iScience 2021 Nov 19;24(11):103274
iScience 2021 Nov 19;24(11):103274
HCRP-1 regulates cell migration, invasion and angiogenesis via Src/ FAK signaling in human prostate cancer.
Chen F, Wu J, Teng J, Li W, Zheng J, Bai J
International journal of biological sciences 2020;16(2):342-352
International journal of biological sciences 2020;16(2):342-352
MicroRNA-19a acts as a prognostic marker and promotes prostate cancer progression via inhibiting VPS37A expression.
Fu F, Wan X, Wang D, Kong Z, Zhang Y, Huang W, Wang C, Wu H, Li Y
Oncotarget 2018 Jan 5;9(2):1931-1943
Oncotarget 2018 Jan 5;9(2):1931-1943
HCRP-1 regulates EGFR-AKT-BIM-mediated anoikis resistance and serves as a prognostic marker in human colon cancer.
Chen F, Zhang L, Wu J, Huo F, Ren X, Zheng J, Pei D
Cell death & disease 2018 Dec 5;9(12):1176
Cell death & disease 2018 Dec 5;9(12):1176
HCRP1 downregulation confers poor prognosis and induces chemoresistance through regulation of EGFR-AKT pathway in human gastric cancer.
Xu H, Miao ZF, Wang ZN, Zhao TT, Xu YY, Song YX, Huang JY, Zhang JY, Liu XY, Wu JH, Xu HM
Virchows Archiv : an international journal of pathology 2017 Dec;471(6):743-751
Virchows Archiv : an international journal of pathology 2017 Dec;471(6):743-751
HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma.
Chen F, Deng J, Liu X, Li W, Zheng J
Scientific reports 2015 Aug 25;5:13470
Scientific reports 2015 Aug 25;5:13470
The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex.
Wunderley L, Brownhill K, Stefani F, Tabernero L, Woodman P
Journal of cell science 2014 Feb 1;127(Pt 3):663-72
Journal of cell science 2014 Feb 1;127(Pt 3):663-72
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
Agromayor M, Soler N, Caballe A, Kueck T, Freund SM, Allen MD, Bycroft M, Perisic O, Ye Y, McDonald B, Scheel H, Hofmann K, Neil SJ, Martin-Serrano J, Williams RL
Structure (London, England : 1993) 2012 Mar 7;20(3):414-28
Structure (London, England : 1993) 2012 Mar 7;20(3):414-28
A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis.
Zivony-Elboum Y, Westbroek W, Kfir N, Savitzki D, Shoval Y, Bloom A, Rod R, Khayat M, Gross B, Samri W, Cohen H, Sonkin V, Freidman T, Geiger D, Fattal-Valevski A, Anikster Y, Waters AM, Kleta R, Falik-Zaccai TC
Journal of medical genetics 2012 Jul;49(7):462-72
Journal of medical genetics 2012 Jul;49(7):462-72
UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting.
Stefani F, Zhang L, Taylor S, Donovan J, Rollinson S, Doyotte A, Brownhill K, Bennion J, Pickering-Brown S, Woodman P
Current biology : CB 2011 Jul 26;21(14):1245-50
Current biology : CB 2011 Jul 26;21(14):1245-50
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 11870-1-AP(VPS37A antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VPS37A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VPS37A. This antibody recognizes human, mouse, rat antigen. The VPS37A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
