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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN784601 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3) (pSer408), (pSer409) antibody
- Antibody type
- Polyclonal
- Antigen
- Phosphopeptide corresponding to amino acid residues surrounding the di-phospho- Ser408/409 of the Rat GABAA receptor, beta-3 subunit.
- Description
- Affinity Chromatography.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Xenopus, Zebrafish
- Host
- Rabbit
- Epitope
- pSer408,pSer409
- Isotype
- IgG
- Vial size
- 0.1 mL
- Storage
- Store the antibody undiluted (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.
GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway.
Molecular and functional diversity of the expanding GABA-A receptor gene family.
Molecular biology of GABAA receptors.
Ogris W, Pöltl A, Hauer B, Ernst M, Oberto A, Wulff P, Höger H, Wisden W, Sieghart W
Biochemical pharmacology 2004 Oct 15;68(8):1621-9
Biochemical pharmacology 2004 Oct 15;68(8):1621-9
GABAA receptor phosphorylation and functional modulation in cortical neurons by a protein kinase C-dependent pathway.
Brandon NJ, Delmas P, Kittler JT, McDonald BJ, Sieghart W, Brown DA, Smart TG, Moss SJ
The Journal of biological chemistry 2000 Dec 8;275(49):38856-62
The Journal of biological chemistry 2000 Dec 8;275(49):38856-62
Molecular and functional diversity of the expanding GABA-A receptor gene family.
Whiting PJ, Bonnert TP, McKernan RM, Farrar S, Le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Thompson SA, Wafford KA
Annals of the New York Academy of Sciences 1999 Apr 30;868:645-53
Annals of the New York Academy of Sciences 1999 Apr 30;868:645-53
Molecular biology of GABAA receptors.
Olsen RW, Tobin AJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990 Mar;4(5):1469-80
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990 Mar;4(5):1469-80
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot of Rat hippocampal lysate showing specific immunolabeling of the ~53k GABAAB3 protein phosphorylated at Serine408/409 (Control). Immunolabeling is blocked by the phospho-peptide (peptide) used as antigen but not by the corresponding dephosphopeptide (not shown).
