Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF1288 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Follistatin-related Gene Protein/FLRG Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects Follistatin-related Gene Protein/FLRG in direct ELISAs and Western blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse FLRG is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
O95633
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Prediction of gestational diabetes mellitus by maternal factors and biomarkers at 11 to 13 weeks.
Nanda S, Savvidou M, Syngelaki A, Akolekar R, Nicolaides KH
Prenatal diagnosis 2011 Feb;31(2):135-41
Prenatal diagnosis 2011 Feb;31(2):135-41
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Supportive validation
- Submitted by
- R&D Systems (provider)
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- Experimental details
- Follistatin-related Gene Protein/FLRG Inhibition of Activin A-induced Hemo-globin Expression and Neutralization by Human Follistatin-related Gene Protein/FLRG Antibody. Recombinant Human Follistatin-related Gene Protein/FLRG (Catalog # 1288-F3) inhibits Recombinant Human/Mouse/Rat Activin A (Catalog # 338-AC) induced hemoglobin expression in the K562 human chronic myelogenous leukemia cell line in a dose-dependent manner (orange line), as measured by the psuedoperoxidase activity. Inhibition of Recombinant Human/Mouse/Rat Activin A (7.5 ng/mL) activity elicited by Recombinant Human Follistatin-related Gene Protein/ FLRG (0.1 µg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human Follistatin-related Gene Protein/FLRG Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1288). The ND50 is typically 1-4 µg/mL.